Will cancer vaccination against human papillomavirus prevent eye cancer disease?
May 15th, 2008 by admin
Department of Ophthalmology, Royal Gwent Hospital, Cardiff Road, Newport NP20 2UB, Wales, UK. david.hughes@gwent.wales.nhs.uk
| cancer |
The role of human papillomavirus (HPV)infection in eye cancer disease is controversial. However, a recent case illustrates the possible role of HPV in conjunctival squamous carcinoma and the potentially devastating effects of this disease. The development of two vaccines to prevent infection with HPV types most commonly cancer associated with anogenital cancers has led to debate about the pros and cons of a national immunisation programme to prevent cervical cancer. The introduction of such a vaccination programme may have an additional cancer beneficial effect on the occurrence of some head and neck, including ocular, cancers. This review discusses the nature of papillomaviruses, cancer mechanisms of infection and cancer carcinogenesis, the possible role of HPV in eye cancer disease, and finally the likely impact of the new prophylactic cancer vaccines.
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